Key Takeways

  • Phase 2 eDREAM data will examine the feasibility of patient-tailored microperimetry as a sensitive functional endpoint for evaluating GAL-101 in geographic atrophy
  • Baseline analyses will explore microperimetry repeatability, structure–function discordance, and agreement between fundus autofluorescence and OCT measurements

Galimedix Therapeutics announced that functional feasibility data from its phase 2 eDREAM study evaluating GAL-101 in geographic atrophy (GA), will be presented at the 26th Euretina Congress. The congress will take place October 1-4, 2026 in Vienna, Austria. The data will showcase the use of patient-tailored microperimetry as a sensitive functional endpoint for evaluating potential treatment effects in the eDREAM study.

The following abstract will be presented by Galimedix:

Oral presentation #1:
Title: Repeatability and Test–Retest Characteristics of Personalized Microperimetry Endpoints in Non-Foveal Geographic Atrophy: Findings from Baseline Triplicate Testing in the eDREAM Trial
Presenter: Yaniv Barkana, MD, Chief Medical Officer, Galimedix
Time/Place: Sunday, October 4 | 12:00-12:06 CEST | Free Paper Forum 1

Other abstracts analyzing baseline data from eDREAM will be presented during the conference:

Oral presentation #2:
Title: Structure–Function Discordance in the Peri-Atrophic Zone of Geographic Atrophy: Baseline Results from the eDREAM Trial
Presenter: Omer Trivizki, MD, MBA, Unit & Deputy Chair of Ophthalmology at Tel-Aviv Medical Center, eDREAM International Coordinating Investigator
Time/Place: Thursday, October 1 | 13:24-13:30 CEST | Free Paper Forum 2

Oral presentation #3:
Title: Cross-modal agreement between FAF and OCT in quantification of geographic atrophy for eyes enrolled in the eDREAM randomised trial
Presenter: Fangyao Tang, Moorfields Ophthalmic Reading Centre & Clinical AI Lab
Time/Place: Friday, October 2 | 16:54-17:00 CEST | Free Paper Forum 1

Oral presentation #4:
Title: Topographic Spatial Agreement Between Fundus Autofluorescence and SD-OCT Features of Geographic Atrophy: Analysis in the eDREAM Trial
Presenter: Yiu Wai Chan, Moorfields Ophthalmic Reading Centre & Clinical AI Lab
Time/Place: Saturday, October 3 | 9:42-9:48 CEST | Free Paper Forum 2

E-Poster #1:
Title: Repeatability and Correlation of Best-Corrected Visual Acuity, Low-Luminance Visual Acuity, and Central Foveal Microperimetry: Baseline Paired-Visit Data from the eDREAM Trial
Presenter: Omer Trivizki, MD, MBA, Unit & Deputy Chair of Ophthalmology at Tel-Aviv Medical Center, eDREAM International Coordinating Investigator
Time/Place: Thursday, October 1| Poster Hub

E-poster #2:
Title: Locus-level test-retest repeatability of MAIA microperimetry in geographic atrophy: implications for trial endpoint design from the eDREAM randomised trial
Presenter: Dun Jack Fu, Moorfields Ophthalmic Reading Centre & Clinical AI Lab
Time/Place: Thursday, October 1 | Poster Hub