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International Study Finds Polygenic Risk Score May Predict Glaucoma Development, Progression, and Surgery Risk image

11.13.2026

International Study Finds Polygenic Risk Score May Predict Glaucoma Development, Progression, and Surgery Risk

New research published in Ophthalmology suggests that a polygenic risk score (PRS) underlying Seonix Bio’s SightScore genetic test may help identify individuals at increased risk of developing glaucoma and predict disease progression and the likelihood of surgical intervention.1 The study evaluated the PRS using genetic data from more than 6.5 million individuals across independent cohorts representing multiple ancestry groups. Across 3 validation datasets, individuals in the highest 10% of genetic risk had approximately 100 times the odds of glaucoma compared with those in the lowest 10%.

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