Oculis Doses First Patient in Phase 3 PIONEER-1 Trial of Privosegtor for Optic Neuritis

Oculis announced that the first patient has been treated in the PIONEER-1 registrational trial evaluating Privosegtor for acute-onset optic neuritis, marking the start of the company’s late-stage clinical program for the investigational neuroprotective therapy. PIONEER-1 is the first of 2 registrational studies in Oculis’ PIONEER program, or "Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation Research." The trial is enrolling a broad population of patients with acute-onset optic neuritis, including those with and without multiple sclerosis (MS).

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A retinal implant system allowing patients with GA to regain some functional central vision vison is approved in Europe; Bausch + Lomb launches a new preloaded IOL delivery system in the US; and we review recent advancements and milestones in the development of novel ophthalmic treatments. Learn more about your ad choices. Visit megaphone.fm/adchoices

How to Thrive as a New Fellow

Early-career ophthalmologists share pearls from training.

Van Kaden Andre, MD; Cameron Clarke, MD; Shibandri Das, MD; and Ricardo Salinas, MD

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Key Takeaways Fellowship is a time of tremendous growth, both professionally and personally. New fellows should ask questions without hesitation and actively seek feedback from their mentors. Setting aside time each day to review the peer-reviewed literature helps form a strong foundation of knowledge. Developing an understanding of business concepts while in fellowship will help shorten the learning curve for new practitioners. GT: What is your favorite or most valuable piece of advice for trainees just beginning glaucoma fellowship? Van Kaden Andre, MD: Embrace the mix of supervision and independence that you will experience as a fellow. The degree of your autonomy can vary in residency, but, in fellowship, you can expect additional medical and surgical responsibilities and new opportunities to manage them with less supervision. This is a good thing! In fellowship, I wanted to become comfortable with how I would function as an independent glaucoma specialist while also benefitting from the valuable knowledge base of my faculty. As the year progressed, I managed more cases independently, reviewed them with faculty, and asked questions in advance to ensure that I was prepared.

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