Trabeculectomy Outcomes Different for Individuals of African vs European Descent

Source: Reuters Health

Individuals of African descent (AD) and those of European descent (ED) tend to have different outcomes after trabeculectomy with mitomycin C, according to a report in JAMA Ophthalmology.

“African descent was associated with higher failure rates and higher incidence of bleb leaks after initial trabeculectomy with mitomycin C compared with European descent. If this is subsequently shown to be a cause and effect, the findings need to be considered when surgical treatment of glaucoma is contemplated in AD patients,” the team writes in JAMA Ophthalmology.

“These findings suggest that new approaches for controlling wound healing after trabeculectomy are needed and that the role of nonfiltering glaucoma surgeries in patients of African descent needs to be investigated,” Dr. Kouros Nouri-Mahdavi of the Stein Eye Institute at the David Geffen School of Medicine at UCLA, in Los Angeles, and colleagues add.

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