Retinal Layer Thinning in MS Advances With Disease Progression

Source: Medscape

People with progressive multiple sclerosis (MS) show accelerated atrophy in inner and outer nuclear layers of the retina compared to those without the disease, offering important new pieces of the puzzle in understanding the changes that occur as MS advances, researchers say, according to a Medscape report.

“We have found that progressive MS is associated with accelerated inner and outer retinal layer atrophy, independently of age and clinical characteristics,” coauthor Elias S. Sotirchos, MD, a clinical and research fellow with Johns Hopkins University School of Medicine in Baltimore, Maryland, told Medscape Medical News.

“This is a novel finding that has important implications for potential utilization of retinal atrophy measures as outcomes in clinical trials in progressive MS, as well as for monitoring patients in clinical practice,” he said.

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