ImprimisRx announced the findings from a randomized contralateral eye study comparing patient outcomes and preferences for a combination therapy with individual eye drop medications after ocular surgery.
The prospective study, published in Clinical Ophthalmology, was conducted at a single site where patients underwent cataract surgery with both eyes and each eye was randomly selected for the test and control group. Subjects were evaluated at day 1, 15, and 30 measuring visual acuities, refraction, intraocular pressure, macular thickness, patient pain and overall patient satisfaction. According to the study, the ImprimisRx combination drop showed similar health outcomes to multiple separately dosed drops, and that the combination drop was unanimously preferred by patients as it was easier to manage, according to ImprimisRx. The study followed 33 patients who underwent cataract surgery and received the combination drop (prednisolone acetate 1%, gatifloxacin 0.5%, and bromfenac sodium 0.075%) in one randomly selected eye, while the other eye received the same individual eye drop medications post-surgery.
It was noted by the investigator, “Enrollment for this study was relatively slow, as it was difficult to find eligible patients willing to use the three different drops instead of the combination drop; the latter is the standard of care in our clinic.”
“Post ocular surgery, patients are usually required to instill multiple topical drops to prevent infection, inflammation, and pain, often with a different bottle used for each drop. For some patients this can be confusing and/or can be burdensome, which could lead to non-compliance and suboptimal health outcomes,” John Saharek, President of ImprimisRx, said in a company news release. “ImprimisRx formulations such as LessDrops provide the unique ability to combine these individual ingredients into one bottle.”