High Dose of Sildenafil Tied to Long-term Retinal Damage in Case Report

Source: Medscape

A patient who took a high dose of the erectile dysfunction drug sildenafil citrate developed long-term, and possibly irreversible, retinal damage with bilateral multicolored photopsia (perceived flashes of light) and erythropsia (red-tinted vision), according to a case report published in the October issue of Retinal Cases & Brief Reports, as reported by Medscape.

Sildenafil is an oral phosphodiesterase-5 (PDE-5) inhibitor commonly used in tablet form (and best known by the brand name Viagra) to treat erectile dysfunction within the dose range of 25 mg to 100 mg taken an hour before sexual activity. Sildenafil is also used to treat pulmonary hypertension at a dosage range of 0.25 mg/kg to 2 mg/kg every 4 to 8 hours.

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