EyePromise announced the introduction of a new and improved formula to its EyePromise Restore line, with the addition of vitamins B6 and B12, folic acid, and Coenzyme Q10 (CoQ10), according to a company news release. Eyepromise Restore is an ocular nutrition supplement formulated to preserve and support vision for individuals concerned with, at-risk for, or in the early stages of age-related macular degeneration (AMD).
“Zeaxanthin, lutein, and several other components that make up EyePromise Restore have been shown to have a protective effect against the progression of retinal damage,” Joseph J. Pizzimenti, OD, FAAO, faculty member at the Rosenberg School of Optometry at the University of the Incarnate Word in San Antonio, Texas, said in the news release.
In an article published in Advances in Ophthalmology and Visual System1, the authors reported that 97.8 percent of patients supplementing with the original EyePromise Restore formulation improved or stabilized their AMD progression and 88.3 percent saw at least a 30-percent increase in macular pigment optical density, a leading risk factor for AMD that affects 78 percent of the U.S. population. “We believe the addition of B6, B12, folic acid, and CoQ10 to EyePromise Restore will complement these already impressive results and help eye care professionals provide important nutritional support to meet their patients’ eye health needs,” notes Dennis Gierhart, Ph.D., co-founder of ZeaVision, the parent company of EyePromise.
“High levels of homocysteine, an amino acid, and B vitamin deficiencies have been linked to a higher risk of AMD,” A. Paul Chous, OD, FAAO, a private practitioner in Tacoma, Washington, said in the news release. “Folic acid, along with vitamins B6 and B12, has been shown in numerous studies to help lower homocysteine levels.” Taking a combination of vitamins B6 and B12 and folic acid also appears to decrease the risk of age-related macular degeneration in women, according to a study published in Archives of Internal Medicine.2 “Women taking the supplements had a 34 percent lower risk of any AMD and a 41 percent lower risk of visually significant AMD,” he adds.
CoQ10, a substance similar to a vitamin, produces energy the body needs for cell growth and maintenance and also provides protection as an antioxidant against cell damage and improves endothelial cell function. It also protects the mitochondria, the powerhouse of retinal cells, which are compromised in those at-risk for or with early AMD. “Many scientists believe that mitochondrial dysfunction of the cells of the neural retina and retinal pigment epithelium (RPE) make the cells more susceptible to oxidative stress, which is a major factor in early pathogenesis of AMD," says Dr. Chous. “CoQ10 has been shown to promote heart and brain health, and emerging research suggests it also supports retinal health.”
- Herman, Kleiner-Goudey, Davis. Case Report of Dietary Supplements Improving Macular Pigment and Visual Function. Advances in Ophthalmology and Visual System, January, 2017 https://medcraveonline.com/AOVS/AOVS-06-00166.pdf
- William G. Christen; Robert J. Glynn; Emily Y. Chew; Christine M. Albert; JoAnn E. Manson. Folic Acid, Pyridoxine, and Cyanocobalamin Combination Treatment and Age-Related Macular Degeneration in Women: The Women's Antioxidant and Folic Acid Cardiovascular Study. Archives of Internal Medicine, 2009; 169 (4): 335 DOI: 10.1001/archinternmed.2008.574