Calcified Nodules Linked to AMD Progression

Source: Medscape

The presence of a specific type of calcified nodule in the retinal drusen of patients with age-related macular degeneration (AMD) is associated with a more than sixfold increased risk for late-stage progression of the disease, a study has shown, according to a Medscape report.

In a cohort of patients with AMD, progression to advanced AMD was observed in those who had histological and imaging evidence of sprawling patterns of polycrystalline hydroxyapatite (HAP) nodules in the extracellular deposits that accumulate in the retina, Anna C.S. Tan, MD, Vitreous Retina Macula Consultants of New York, New York City, and colleagues report in a research article published online November 7 in Science Translational Medicine.

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