Boost Epi-On Corneal Cross-Linking Data to Be Presented at ESCRS

Source: Avedro

Avedro announced the inclusion of a wide array of Boost Epi-On cross-linking (CXL) presentations in the scientific and educational programs at the 10th EU Cornea Congress and the 37th Congress of the European Society of Cataract and Refractive Surgeons (ESCRS).

These presentations will unveil the early clinical experiences of several clinicians from multiple geographies who have evaluated the company’s next-generation corneal cross-linking treatment for keratoconus.

Boost Epi-On CXL, a novel noninvasive corneal cross-linking procedure that does not require removal of the epithelium addresses the limitations of prior epi-on procedures through the addition of supplemental oxygen. Supplemental oxygen drives oxygen diffusion across the epithelium to enhance cross-linking which stabilizes and strengthens the cornea, ultimately halting or slowing disease progression. Avedro is conducting a pivotal phase 3 clinical trial to evaluate a similar version of the Epi-On procedure in the United States for the treatment of progressive keratoconus. Enrollment was completed earlier this year.

“We believe that Boost Epi-On will increase adoption of cross-linking outside the United States because the application will appeal to patients and clinicians seeking a non-invasive procedure for keratoconus,” Reza Zadno, PhD, Chief Executive Officer of Avedro, said in a company news release. “What’s more, we believe the scientific presentations, coupled with Avedro’s programs at ESCRS, provide an ideal venue to educate ophthalmologists on this new technology.”

Physicians attending EU Cornea and ESCRS, held on September 14-18 in Paris, France, will have numerous opportunities to learn how Boost Epi-On CXL may benefit patients and ophthalmology practices. Clinical efficacy data and preclinical research will be presented during the main scientific program, and Avedro will also host a series of peer-to-peer group discussions and a satellite symposium. The full event schedule is below.

Relevant Avedro Activities at ESCRS Friday, September 13

  • 12:15 – 12:30 PM – Advances in Cross-Linking: Epi-On Cross-Linking with Supplemental Oxygen Francois Malecaze, PhD, Room: North 4

  • 7:05 – 7:12 PM – Epi-On Epi-Off Debate in the Advent of New Technologies Miltos Balidis, MD, Room West 3/Level 7.3

  • 7:12 – 7:19 PM – A Prospective Study on Epi-On CXL Using Supplemental Oxygen Francois Malecaze, MD, PhD, Room West 3/Level 7.3

    Saturday, September 14

    • 10:00 – 10:30 AM – Boost Epi-On Meet the Experts Miltos Balidis, MD, PhD, Avedro Booth B100

    • 3:00 – 3:30 PM – Boost Epi-On Meet the Experts Miguel Rechichi, MD, PhD, Avedro Booth B100

    • 6:00 – 7:45 PM – ESCRS Satellite Symposium: Beyond Barriers: Boost Epi-On CXL with Oxygen Cosimo Mazzota, MD, PhD, Miltos Balidis, MD, PhD, Francois Malecaze, MD, PhD, Brendan Cronin, MD, and Raj Rajpal as moderator. Reception and Program at Paris Expo, Porte de Versailles – West 6 (ESCRS Congress Venue).

      Sunday, September 15

• 2:00 – 2:30 PM – Boost Epi-On Meet the Experts Brendan Cronin, MD, Avedro Booth B100

Monday, September 16

• 4:18 – 4:24 PM – Impact of Oxygen, UV parameters and Drug Formulation on Accelerated Epi-On Corneal Cross-Linking Desmond Adler, PhD, Abstract Room South 5

For more information, visit Avedro booth #B100 at ESCRS.

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